Job summary

About the role:

Help us see cancer like never before.

We are looking for a keen and collaborative postdoctoral with a background in computational biology or bioinformatics to join an exciting new joint project between the UCL institute and HSL Pathology Ltd.

This is a unique chance to work on T-Cell lymphomas, using spatial transcriptomics to explore tumour biology in unprecedented detail. You will be based the Halo Building in the heart of the Kings Cross Knowledge Quarter, working alongside HSL specialised Laboratory scientists and UCL research team led by Professor Tariq Enver, Dr Rajeev Gupta and Dr Sam Marguerat.

Whats the project about?

This role focuses on understanding the biology of T-Cell using spatial transcriptomics and high dimensional data. You will:

Generating and analysing large spatial transcriptomics datasets from clinical samples.
Collaborate with laboratory scientists to bring together computational and experimental data.
Carry out meta- analysis of flow cytometry datasets across a broader patient cohort.
Contribute to identifying new biomarkers and exploring spatial tech in diagnostics.

Main duties of the job

Who are we looking for?

A PhD (or nearly there) in computational biology, bioinformatics or related field.
Candidates with a theoretical background in physics or mathematics are encouraged to apply.
Experience with either Spatial transcriptomics or scRNAseq data analysis.
Solid coding skills in R, Bash and Perl or Python.
A collaborative mindset happy working across clinical and academic settings.

Why join us?

Because this isnt a run -of the- mill postdoc. You will be a part of a brand- new translational collaboration with room to shape the project and make a real impact.

This is a 2-year fixed term post, giving you the chance to work intensively on a focused, well-defined project that bridges cutting -edge computational biology, cancer research and clinical diagnostics.

You will be based at the Halo building, a modern purpose- built lad and office space in the heart of Kings Cross one of Londons most dynamic and well-connected areas. With major transport link, great food and green spaces and a growing life sciences hub right on your doorstep, its a fantastic place to work.
Access state-of-the-art lab and computational facilities.
Be part of a genuinely collaborative team spanning academia and diagnostics.
Contribute to research that could shape the future of T-Cell lymphoma diagnostics.

About us

At HSL we offer a variety of excellent staff benefits including:

Training and development opportunities supporting professional development

Annual performance related salary review

** No banding restrictions:**As we are a private company we are not restricted by salary bandings and so are able to negotiate appropriate salaries based on experience. This also means that annual salary reviews do not hit a band ceiling.

Discounted gym membership we have a corporate gym membership scheme with Better Gyms

Cash healthcare plan cash back on a variety of healthcare costs including dentist and opticians

Sick Pay Entitlement 5 paid days in the first year of employment, 20 days thereafter

Permanent Health Insurance and Death in Service Cover

Life Assurance providing salary continuation for long term illness (six months qualifying period)

Employee Assistance Programme supporting staff wellbeing

Season Ticket Loan Scheme interest free loan for the cost of annual travel ticket

Perkbox Access to additional staff perks and benefits such as high street discounts

Company Pension Scheme company and staff contributions which increase with service

Competitive annual leave allowance-23 days rising to 28 days after 5 years service

Flexible working hours 40 hours standard working week

Job description

Job responsibilities

Main Duties:To include, but not be restricted to, the following duties:1. Contribute in all phases of the project lifecycle, from study design to publication.2. Plan, develop and carry out original research.3. To conduct data analysis ensuring its validity and reliability of data at all times. 4. To handle confidential data responsibly and ensure that confidentiality is maintain when applicable.5. To have good awareness of the Human Tissue Act and to work according to it.6. To maintain accurate and complete records of all findings.7. Keep abreast of relevant literature and methodology developments relevant to the field.8. Work collaboratively.9. Communicate with both HSL and UCL and other group members on a regular basis to discuss projects updates.10.Attend regular laboratory meetings and interact collaboratively with other scientific staff.11. Attend appropriate scientific seminars, meetings, conferences and relevant training opportunities.12. Participate in the activities of the group and department, contributing scientific ideas and innovative solutions.13. To develop contacts and research collaborations within the institute and research fields.14. Provide guidance as required to support staff and any students who may be assisting with research.15. To help prepare and submit grants to appropriate funders.16. To maintain awareness of health and safety regulations; to make sure all risk assessments are up-to-date and to ensure that all codes of practice are being followed.17.As duties and responsibilities change, the job description will be reviewed and amended in consultation with the post holder.18. The postholder will carry out any other duties as are within the scope, spirit and purpose of the job as requested by the line manager.

Job description
Job responsibilities

Main Duties:To include, but not be restricted to, the following duties:1. Contribute in all phases of the project lifecycle, from study design to publication.2. Plan, develop and carry out original research.3. To conduct data analysis ensuring its validity and reliability of data at all times. 4. To handle confidential data responsibly and ensure that confidentiality is maintain when applicable.5. To have good awareness of the Human Tissue Act and to work according to it.6. To maintain accurate and complete records of all findings.7. Keep abreast of relevant literature and methodology developments relevant to the field.8. Work collaboratively.9. Communicate with both HSL and UCL and other group members on a regular basis to discuss projects updates.10.Attend regular laboratory meetings and interact collaboratively with other scientific staff.11. Attend appropriate scientific seminars, meetings, conferences and relevant training opportunities.12. Participate in the activities of the group and department, contributing scientific ideas and innovative solutions.13. To develop contacts and research collaborations within the institute and research fields.14. Provide guidance as required to support staff and any students who may be assisting with research.15. To help prepare and submit grants to appropriate funders.16. To maintain awareness of health and safety regulations; to make sure all risk assessments are up-to-date and to ensure that all codes of practice are being followed.17.As duties and responsibilities change, the job description will be reviewed and amended in consultation with the post holder.18. The postholder will carry out any other duties as are within the scope, spirit and purpose of the job as requested by the line manager.

Person Specification

Qualifications

Essential

PhD in a relevant subject

Experience

Essential

Proven track record of scientific publication and conference presentations. Excellent knowledge of R, Bash and Perl or Python.
Experience with either Spatial transcriptomics or scRNA-seq data analysis.
Experience with handling large datasets.

Person Specification
Qualifications

Essential

PhD in a relevant subject

Experience

Essential

Proven track record of scientific publication and conference presentations. Excellent knowledge of R, Bash and Perl or Python.
Experience with either Spatial transcriptomics or scRNA-seq data analysis.
Experience with handling large datasets.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .

Additional information
Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .

Employer details

Employer name

Health Services Laboratories
Address

Health Services Laboratory

1 Mabledon Place

London

WC1H 9AX

Employer's website

Health Services Laboratories

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